Bernhard Hellmich Selected Research

Felty Syndrome (Syndrome, Felty's)

4/2012	Felty's syndrome autoantibodies bind to deiminated histones and neutrophil extracellular chromatin traps.
9/2002	Autoantibodies against granulocyte colony-stimulating factor in Felty's syndrome and neutropenic systemic lupus erythematosus.
8/2002	Low Fcgamma receptor III and high granulocyte colony-stimulating factor serum levels correlate with the risk of infection in neutropenia due to Felty's syndrome or systemic lupus erythematosus.

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Bernhard Hellmich Research Topics

Disease

21	Vasculitis (Vasculitides) 05/2022 - 07/2003
13	Granulomatosis with Polyangiitis (Wegener's Granulomatosis) 05/2022 - 02/2004
9	Churg-Strauss Syndrome (Allergic Angiitis) 02/2022 - 01/2004
8	Microscopic Polyangiitis 05/2022 - 12/2005
6	Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis 05/2022 - 03/2006
5	Infections 04/2022 - 08/2002
5	Systemic Lupus Erythematosus (Libman-Sacks Disease) 02/2022 - 08/2002
5	Rheumatoid Arthritis 04/2012 - 08/2002
4	Giant Cell Arteritis (Horton Disease) 02/2022 - 01/2020
3	Asthma (Bronchial Asthma) 01/2021 - 01/2004
3	Autoimmune Diseases (Autoimmune Disease) 11/2020 - 12/2005
3	Systemic Vasculitis 05/2020 - 03/2006
3	Rheumatic Diseases (Rheumatism) 01/2017 - 08/2002
3	Felty Syndrome (Syndrome, Felty's) 04/2012 - 08/2002
2	Systemic Scleroderma (Systemic Sclerosis) 02/2022 - 01/2011
2	Vascular Diseases (Vascular Disease) 02/2022 - 02/2006
2	Connective Tissue Diseases (Connective Tissue Disease) 02/2022 - 02/2006
2	Disease Progression 06/2013 - 12/2005
2	Polyarteritis Nodosa (Periarteritis Nodosa) 02/2007 - 12/2005
2	Neutropenia 09/2002 - 08/2002
1	Cryoglobulinemia 04/2022
1	Interstitial Lung Diseases (Interstitial Lung Disease) 02/2022
1	Lupus Nephritis 02/2022
1	Aneurysm (Aneurysms) 05/2021
1	Pathologic Constriction (Stenosis) 05/2021
1	Peripheral Nervous System Diseases (PNS Diseases) 01/2021
1	Virus Diseases (Viral Diseases) 11/2020
1	Kidney Diseases (Kidney Disease) 06/2020
1	Hemorrhage 06/2020
1	Purpura 06/2020
1	Skin Manifestations 06/2020
1	Polyneuropathies (Polyneuropathy) 06/2020
1	Glomerulonephritis 06/2020
1	Cytopenia 01/2020
1	Agammaglobulinemia (Hypogammaglobulinemia) 01/2020
1	Takayasu Arteritis (Arteritis, Takayasu's) 01/2020
1	Fever (Fevers) 01/2018
1	Ulcer 01/2011
1	digital ulcers 01/2011
1	Seizures (Absence Seizure) 11/2010
1	Rheumatoid Vasculitis 12/2007
1	Pleural Effusion (Pleural Effusions) 09/2007
1	Tuberculosis (Tuberculoses) 09/2007
1	Chronic Disease (Chronic Diseases) 06/2007
1	Crohn Disease (Crohn's Disease) 06/2006
1	Granuloma 06/2006
1	Arteritis 03/2006
1	Type 1 Diabetes Mellitus (Autoimmune Diabetes) 12/2005
1	IgA Vasculitis (Purpura, Schoenlein Henoch) 12/2005
1	Immunologic Deficiency Syndromes 12/2005

Drug/Important Bio-Agent (IBA)

17	Antineutrophil Cytoplasmic Antibodies (ANCA)IBA 05/2022 - 07/2003
6	Prednisone (Sone)FDA LinkGeneric 01/2022 - 12/2005
6	AutoantibodiesIBA 04/2012 - 09/2002
5	Rituximab (Mabthera)FDA Link 05/2022 - 01/2017
4	GlucocorticoidsIBA 04/2022 - 01/2020
4	Methotrexate (Mexate)FDA LinkGeneric 01/2022 - 01/2004
4	Biomarkers (Surrogate Marker)IBA 05/2020 - 02/2007
3	Cyclophosphamide (Cytoxan)FDA LinkGeneric 01/2010 - 12/2005
2	belimumabIBA 04/2022 - 02/2022
2	CollagenIBA 02/2022 - 02/2006
2	Prednisolone (Predate)FDA LinkGeneric 01/2022 - 09/2007
2	Edetic Acid (EDTA)FDA Link 01/2022 - 01/2017
2	AntigensIBA 06/2020 - 01/2018
2	Myeloblastin (Proteinase 3)IBA 06/2006 - 02/2004
2	Biological ProductsIBA 03/2006 - 10/2003
2	Azathioprine (Imuran)FDA LinkGeneric 03/2006 - 01/2006
2	Granulocyte Colony-Stimulating Factor (G-CSF)IBA 09/2002 - 08/2002
1	Prostaglandins AIBA 05/2022
1	Alkylating AgentsIBA 04/2022
1	tocilizumab (atlizumab)FDA Link 02/2022
1	Immunosuppressive Agents (Immunosuppressants)IBA 02/2022
1	B-Cell Activating FactorIBA 02/2022
1	InterleukinsIBA 02/2022
1	mavrilimumabIBA 01/2022
1	mepolizumabIBA 01/2022
1	Granulocyte-Macrophage Colony-Stimulating Factor (GM-CSF)IBA 01/2022
1	AntibodiesIBA 06/2020
1	C-Reactive ProteinIBA 01/2018
1	Antirheumatic Agents (DMARD)IBA 01/2018
1	Mycophenolic Acid (Cellcept)FDA LinkGeneric 01/2017
1	Histones (Histone)IBA 04/2012
1	ChromatinIBA 04/2012
1	Interleukin-5 (Interleukin 5)IBA 09/2011
1	Bosentan (Tracleer)FDA Link 01/2011
1	Oxygen (Dioxygen)IBA 11/2010
1	Interferon-alpha (Interferon Alfa)IBA 01/2010
1	AutoantigensIBA 06/2006
1	Antigen-Antibody Complex (Immune Complex)IBA 03/2006
1	Infliximab (Remicade)FDA Link 01/2006
1	Leflunomide (Arava)FDA LinkGeneric 01/2006
1	CytokinesIBA 01/2006
1	Tyrosine (L-Tyrosine)FDA Link 12/2005
1	Phosphoric Monoester Hydrolases (Phosphatases)IBA 12/2005
1	Intravenous Immunoglobulins (IVIG)FDA Link 12/2005

Therapy/Procedure

12	Therapeutics 02/2022 - 10/2003
3	Remission Induction 01/2020 - 01/2010
1	Duration of Therapy 05/2021
1	Precision Medicine 05/2020
1	Contraindications 01/2010
1	Lasers (Laser) 12/2007